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Wednesday, May 30, 2018

Health Benefits of Fruit

Modern lifestyle diseases, like obesity and metabolic syndrome (MS), can lead to many complications, including hypertension, diabetes, hyperlipidemia and cardiovascular disease. They also accelerate the course of aging processes. Appropriate dietary interventions can help regulate glucose and energy metabolism, and thus improve the outcome for affected individuals.

Among the interventions is a caloric restriction, which helps reduce insulin resistance by preventing suffered hyperglycemia. This often requires long-term management of the dietary size of choice and the part that is difficult to maintain for most complete questions. For this reason, functional foods, like passion fruit are being studied for their potential contribution to reducing the resistance of weight and insulin.

Metabolic benefits
One mixture is in the fruit of passion, which has stored a lot of interest in piceatannol, an analog of resveratrol. Latter polyphenol, which was shown to lower glucose levels, and to increase endurance, in several rodent studies.

A clinical study on resveratrol in people with an excessive-high body mass index (BMI) confirmed these results, as well as its ability to produce a decrease in blood pressure and higher mitochondrial breathing in muscle tissue, as well as the activation of several muscle kinases. Piceatannol shares many of these benefits, improving metabolic parameters and breakdown of glucose, reducing vascular tone, increasing levels of eNOS (which is vaso-protective), promoting collagen synthesis, and reducing ultraviolet damage to the skin. In fact, its activity is higher than the activity of resveratrol.

One study showed that insulin levels in the serum were significantly reduced in a fasting state in total people with the addition of piceatannol, as well as a drop in blood pressure and heart rate. This was not seen in women or in people with normal BMI. Another study in mice showed the inhibition of postprandial ascents in blood glucose levels as well, which points to the potential for antidiabetic activity with piceatannol supplements. Further studies are needed to understand the change in effect with the composition and genus of the body, as well as performing more sensitive and longer-term assessments of changes in glucose and insulin parameters.

Cardiovascular benefits
Cardiovascular effects of piceatannol antioxidant and anti-inflammatory effects of polyphenol seem to mediate. It is known that the failure of vasorelaxation, which is mediated by eNOS activity, is characteristic of endothelial dysfunction. This would lead finally to atherosclerosis through lipid oxidation and inflammation of the blood vessels. It also activates the dimethylaminohydrolase of dimethylarginine, and thus blocks the natural shutdown of eNOS. Again, it increases the stability of the eNOS, thereby increasing its half-life. It has other mechanisms of vascular anti-inflammatory action as well. Piceatannol thus has profound cardioprotective effects, and the central mechanism of action cannot be managed out either. In addition, it can help stabilize cardiac myocytes.

Each serving 100g of passion fruit supplies about 30g potassium, or a quarter of a daily requirement. This is one of the best things to do to reduce cardiovascular risk. Potassium is a vasodilator and is necessary for the activity of significant ion channels in the cell membranes.

Antioxidant benefits
The passion fruit also contains many other antioxidants, like C-glycosyl flavonoids, chlorogenic acid, isovitexin, caffeic acid, quercetin, rutin, and luteolin. These also play a role in the management of glycemic and lipid, but precise effects and doses should be clarified through further study. A single serving can contain about 30g vitamin C, and significant quantities of carotene and cryptoxanthin, which are powerful antioxidant molecules lowering the risk of time-related degeneration, cancers, and cardiovascular disease. Vitamin C also stimulates collagen synthesis and improves epithelial health, as well as an immunomodulator in order to boost congenital immunity.

Dietary fiber
Passion fruits also contain a large amount of dietary fiber (98% of the daily intake), which helps improve intestinal health, reduce pH and amyoc level in the colon and thus encourage healthy intestinal microbiota, and relieve constipation and flatulence. Again, fiber reduces appetite and this again leads to lower insulin levels and the reversal of metabolic syndrome. It also results in lower cholesterol levels in the blood. Fruit rind is also rich in fiber soluble, which has independent antidiabetic and anti-dyslipidemic effects. Fiber also lowers the risk of colorectal cancer. Piceatannol also counteracts the irritation of colonic leading to intestinal inflammation.

Eye Health
A large amount of vitamin A in the fruit of passion can guarantee eye health against time-related macular degeneration, prevent cataracts, and lower the rate of aging and wrinkling of the skin.

Anemia
The passion fruit also contains an appreciable amount of copper, iron, magnesium, and phosphorus, contributing to bone health and to normal RBC counts, which helps counter anemia.

Advantages of Anxiolytic
Some rodent studies found a marked anxiolytic and sedative effect on supplementing the diet with passion fruit, due to Harman alkaloid. It can also help relieve insomnia.

Advantages of Anti-Tumor
Anti-cancer effects include apoptotic effects on the lines of the human cancer cell, as well as inhibition of migration and epithelial anchoring of metastatic cells in breast and prostate cancer. Piceatannol also blocks the understanding of HDL by neurons to which the autoantibodies ecto-F1-ATPase are bound. It can thus slow down the development and progression of Alzheimer's disease. It can also block the antigen-induced WBC degranulation and thus prevent allergic reactions.

Conclusion
The passion fruit is not just a very tasty tropical addition to the menu, but the powerhouse has several potential health benefits and should become part of a varied and rich diet when available in the season.


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